Southeastern Colorado is under an air quality health advisory issued by the Colorado Department of Public Health and Environment due to significant wildfire smoke. The advisory, effective from 4 p.m. Friday to 9 a.m. Saturday, covers counties including Kit Carson, Cheyenne, Kiowa, Crowley, Otero, Bent, Prowers, and Pueblo, impacting communities like Burlington, Cheyenne Wells, Eads, Ordway, La Junta, Las Animas, Lamar, and Pueblo. Residents are advised to remain indoors to minimize exposure to the smoke, which contains fine particulate matter harmful to breathe, especially for vulnerable populations. Symptoms of exposure include coughing, wheezing, and shortness of breath.