Residents of the Northern Plains and Great Lakes regions should brace themselves for a weekend of heavy snow, strong winds, and frigid temperatures. A significant winter storm is poised to impact the area, bringing with it hazardous travel conditions and the potential for blizzard-like conditions. Lake-effect snow will be a major factor, particularly in areas downwind of the Upper and Lower Great Lakes. Chicago is forecast to receive between 6 and 12 inches of snow, while Marquette, Michigan, could see over a foot of accumulation by Tuesday morning.