The intensification of lake anoxia poses significant risks to aquatic ecosystems and human water resources. Prolonged oxygen depletion in lake hypolimnia can lead to biodiversity loss, reduced fish yields, and increased greenhouse gas emissions. Eutrophic lakes, which are already nutrient-rich, are particularly at risk, with up to 90% projected to experience anoxia under severe climate scenarios. Oligotrophic lakes, while more resilient, are not immune, with hypoxia expected to affect up to 75% of these systems by the century's end. These changes could also increase the cost and complexity of water treatment for human consumption.